Assessment of Serum Luteinizing Hormone, Follicle Stimulating Hormone and Esteradiol Levels among Sudanese Infertile Females

Background and Objective: As infertility is rapidly becoming a major medical problems among Sudanese females, that has an impact on ovulation and menstruation and other complications, the aim of our present study to investigate the concentration and evaluate potential role of luteinizing hormone, follicle stimulating hormone and esteradiol in Sudanese infertile females, that may help and facilitate the diagnosis and flow up of this problem. Materials and Methods: A prospective, analytic, crosssectional and hospital-based study included Sudanese females live in KhartoumStateSudan, in period from March 2012 to May 2014. A total of tow hundred infertile Sudanese females were compared with one hundred fertile females as control group, all of them were age matched , Samples were taken from test and control group in morning after overnight fasting, then serum luteinizing hormone(LH), follicle stimulating hormone(FSH) and esteradiol(E2) levels were analyzed using ELISA technique. Results: The (mean ± SD) of serum luteinizing hormone (LH), follicle stimulating hormone (FSH) and esteradiol (E2) levels in infertile Sudanese females were14.60±9.8μIU/ml, 6.51±2.048μIU/ml and 89.61±9.37 Pg/ml respectively. While that of fertile females (control group), the (mean ± SD) of serum luteinizing hormone, follicle stimulating hormone and esteradiol, were 7.00±5.26 μIU/ml, 8.13±3.88 μIU/ml,56.93±10.3 Pg/ml respectively. Serum levels of luteinizing hormone and esteradiol were significantly elevated in infertile females when compared with control group (P<0.05, serum level of follicle stimulating hormone was decreased (P>0.05). Conclusion: Patients with infertility have significant increase levels of Serum of luteinizing hormone, esteradiol and serum follicle stimulating hormone level was reduced.